WebMar 2, 2024 · Cryptotanshinone (CPT), as a major component of Salvia miltiorrhiza Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. However, the exact cellular and molecular mechanisms of the anti-inflammatory activities of CPT remain to be elucidated. The present study was aimed to clarify its mechanisms on … Web別名: クリプトタンシノン. タンシノンC. ( R )-1,2,6,7,8,9-ヘキサヒドロ-1,6,6-トリメチルフェナントロ [1,2- b ]フラン-10,11-ジオン. Tanshinone C. ( R )-1,2,6,7,8,9-Hexahydro-1,6,6 …
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WebIn vivo, cryptotanshinone attenuates caspase-1 activation and IL-1β secretion in mouse models of NLRP3 inflammasome-mediated diseases such as endotoxemia syndrome and methionine- and choline-deficient-diet-induced nonalcoholic steatohepatitis (NASH). Our findings suggest that cryptotanshinone may be a promising therapeutic agent for the ... WebSep 2, 2024 · 2.1. Cryptotanshinone Delayed Progressive Paralysis of AD C. elegans and Decreased the Ratio of Exogenous Serotonin-Induced Acute Paralysis . Aβ-induced neurotoxicity is one of the most important features of Alzheimer’s disease [].To further evaluate the effect of CTS treatment on Aβ-induced pathology, a temperature-sensitive C. … iowa state football news 2021
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WebMar 10, 2024 · Cryptotanshinone (CTS) is a lipophilic constituent of Salvia miltiorrhiza, with a broad-spectrum anticancer activity. We have observed that CTS enhances the efficacy of gefitinib in human lung cancer H1975 cells, yet little is known about its molecular mechanism. To explore how CTS enhances H1975 cell sensitivity to gefitinib, we figured … WebJan 14, 2024 · Interestingly, cryptotanshinone and senkyunolide I, two representative compounds respectively derived from the two herbs, also showed synergistic antithrombotic effects. Further analysis suggested that they may regulate thrombi formation at different levels via multiple signaling pathways, including oxidative stress, platelet activation and ... WebJul 1, 2024 · Abstract. Cryptotanshinone is a diterpene quinone derived from the roots of Salvia miltiorrhiza Bunge. An increasing number of studies have demonstrated that cryptotanshinone has the pharmacological activities such as anti-oxidative stress, anti-bacteria, anti-inflammation, and anti-cancer. Cryptotanshinone has been found to … opengl draw points