WebJul 1, 2004 · The extraneuronal monoamine transporter Slc22a3/Orct3 co-localizes with the Maoa metabolizing enzyme in mouse placenta. Mech Dev (2001) S.D Sivasubramaniam et al. Monoamine oxidase expression and activity in human placentae from pre-eclamptic and normotensive pregnancies. Placenta WebTwo recently described organic cation transporter genes, Slc22a2 (Orct2) and Slc22a3 (Orct3), fulfill criteria predicted for t(w73) candidate genes, since both map to the …
The oct3 gene, a gene for an embryonic transcription factor, is ...
Web(B) Orct3 expression in wild-type and homozygous mutant mouse placentas at different stages of development. The 3.5-kb wild- type and 2.8-kb aberrant transcripts are indicated. Pai-1 hybridization ... WebJan 25, 2024 · The anthracycline doxorubicin is commonly used in many regimens for the treatment of solid tumors and hematological malignancies (1, 2).The clinical utility of doxorubicin is limited by the onset of dose-dependent and irreversible cardiac injury that predisposes patients to an increased risk for congestive heart failure (1–3).The apparent … body and mind spa belgrade
Morphology and gene expression in mouse placentas lacking …
WebEMT, Oct, Orc, Oct3, Orct3, Slca22a3: NCBI Gene Id: 20519: Protein Name: Solute carrier family 22 member 3: Description of Target: Slc22a3 mediates potential-dependent transport of a variety of organic cations. It may play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain. Uniprot ID: Q9WTW5 ... WebImportant clinical substrates include metformin and cisplatin. Gene polymorphisms of OCT2 are associated with altered metformin and cisplatin pharmacokinetics and toxicity, but the … WebJul 1, 2001 · Since Orct3 is not expressed in embryonic tissue, these data indicate that Orct3 is the rate-limiting step in MPP + transport from the placenta to the fetus but does not … body and mind seaside